Best Yellow Squash Casserole Recipe for a Classic Southern Comfort Dish

If you love classic comfort food with a touch of Southern charm, you need a good yellow squash casserole recipe in your kitchen. This dish has been a favorite at potlucks, holiday tables and Sunday dinners for generations. It’s warm, cheesy, buttery and makes the perfect side for almost any meal.

Yellow squash casserole is simple but satisfying. Fresh summer squash gets cooked down with onions, mixed with a creamy, cheesy filling, and topped with buttery crumbs that bake up golden and crisp. The result is a dish that makes everyone come back for seconds.

Why Make Yellow Squash Casserole?

Yellow squash is mild, slightly sweet and easy to find in warm months. If you have a garden full of squash or grab a few from the farmers market, this casserole is one of the best ways to use it up. It’s also budget-friendly and pairs well with chicken, pork chops, barbecue or even a holiday ham.

This version keeps the ingredients simple but big on flavor, so you can serve it any time you need an easy side that feels special.

Ingredients for Yellow Squash Casserole

Here’s what you’ll need for a classic squash casserole:

• 4 cups sliced yellow squash (about 4 medium squash)
• 1 small onion, finely chopped
• 1 cup shredded sharp cheddar cheese
• ½ cup grated parmesan cheese
• ½ cup sour cream
• 1 large egg, beaten
• 2 tablespoons butter
• 1 cup breadcrumbs or crushed buttery crackers
• 2 tablespoons butter, melted (for topping)
• ½ teaspoon garlic powder
• ½ teaspoon salt
• ¼ teaspoon black pepper

How to Make Yellow Squash Casserole

Step 1: Prep the Squash

Wash and slice the yellow squash into thin rounds. Try to keep them about the same thickness so they cook evenly.

In a large skillet over medium heat, melt 2 tablespoons of butter. Add the squash and chopped onion. Cook for about 8 to 10 minutes, stirring occasionally, until the squash is tender and most of the moisture has cooked out.

Drain any excess liquid from the squash mixture to keep your casserole from getting watery.

Step 2: Mix the Filling

In a large bowl, combine the cooked squash and onions with shredded cheddar, parmesan, sour cream, beaten egg, garlic powder, salt and pepper. Stir until everything is well mixed.

The cheeses and sour cream make the filling creamy and rich, while the egg helps bind it all together.

Step 3: Assemble the Casserole

Preheat your oven to 350°F (175°C). Lightly grease a medium baking dish. Spoon the squash mixture into the dish and spread it evenly.

In a separate small bowl, mix the breadcrumbs or crushed crackers with the melted butter. Sprinkle this topping evenly over the casserole.

Step 4: Bake Until Golden

Bake for 25 to 30 minutes, or until the topping is golden brown and the casserole is bubbling around the edges.

Let it rest for a few minutes before serving so it sets up nicely and scoops out easily.

Tips for the Best Squash Casserole

• Use fresh yellow squash that’s firm and bright for the best flavor.
• If you want extra crunch, mix in some crushed Ritz crackers with the breadcrumbs.
• For a sharper taste, try a mix of cheddar and a bit of pepper jack cheese.
• To make it more filling, add a handful of cooked rice to the mixture.
• If you want a gluten-free version, swap the breadcrumbs for gluten-free crumbs or crushed gluten-free crackers.

How to Store and Reheat

Yellow squash casserole is just as good the next day. Store leftovers in an airtight container in the fridge for up to 3 days.

To reheat, cover with foil and warm it in the oven at 350°F until hot. You can also microwave individual portions for a quick side dish.

Make It Ahead

This casserole is great for meal prep and holidays. You can assemble it a day ahead, cover tightly and keep it in the fridge. When ready to bake, add the topping and pop it in the oven. This saves time when you have a big meal to prepare.

What to Serve with Squash Casserole

This dish goes with just about everything. Serve it alongside:

• Grilled or roasted chicken
• Pork chops or roast pork loin
• Baked or fried fish
• BBQ ribs or pulled pork sandwiches
• A big green salad for a lighter meal

Final Bite

Yellow squash casserole is a true Southern classic that brings comfort and warmth to any table. It’s easy enough for a weeknight dinner but special enough for a holiday side dish. The creamy filling, melted cheese and crispy topping make every bite a taste of home.

Next time you’re looking for a simple recipe to use up summer squash, give this casserole a try. It’s proof that a few simple ingredients and a little love can turn humble squash into a dish that always gets rave reviews.